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Human Tumor Necrosis Factor Receptor Superfamily Member 1A (TNFRSF1A) ELISA Kit
Human Tumor Necrosis Factor Receptor Superfamily Member 1A (TNFRSF1A) ELISA Kit
This ELISA kit is designed to detect Human Tumor Necrosis Factor Receptor Superfamily Member 1A (Human TNFRSF1A). The assay plate has been pre-coated with mouse anti-Human TNFR1 monoclonal antibody. When the sample containing TNFR1 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human TNFR1 Antibody is added to the wells and binds to TNFR1 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human TNFR1 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE144
Regular price
$624.00 USD
Regular price
$480.00 USD
Sale price
$624.00 USD
Unit price
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per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
1.78 pg/mL
Detection Range
7.81-500 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Cancer, Cardiovascular, Cell Biology, Immunology, Signal Transduction, Stem cells
Background
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Tumor necrosis factor receptor superfamily member 1A
Regulatory Status
For Research Use Only
