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Human Vascular Endothelial Growth Factor Receptor 3 (FLT4) ELISA Kit
Human Vascular Endothelial Growth Factor Receptor 3 (FLT4) ELISA Kit
This ELISA kit is designed to detect Human Vascular Endothelial Growth Factor Receptor 3 (Human FLT4). The assay plate has been pre-coated with mouse anti-Human VEGFR3 monoclonal antibody. When the sample containing VEGFR3 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human VEGFR3 Antibody is added to the wells and binds to VEGFR3 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human VEGFR3 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE134
Regular price
$624.00 USD
Regular price
$480.00 USD
Sale price
$624.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
18.83 pg/mL
Detection Range
78.13-5000 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Cancer, Cardiovascular, Neuroscience, Signal Transduction
Background
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of Signal transduction . The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Vascular endothelial growth factor receptor 3
Regulatory Status
For Research Use Only
