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Recombinant Rhesus Macaque B7-H4 (C-Fc)
Recombinant Rhesus Macaque B7-H4 (C-Fc)
Recombinant Rhesus Macaque V-set Domain-containing T-cell Activation Inhibitor 1 is produced by our Mammalian expression system and the target gene encoding Phe29-Ala258 is expressed with a Fc tag at the C-terminus.
Catalog No:
EPT264
Regular price
$1,065.00 USD
Regular price
$819.00 USD
Sale price
$1,065.00 USD
Unit price
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per
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Product Details
Accession
F7B770
Molecular Weight
52.5 KDa
Apparent Molecular Weight
70-100 KDa, reducing conditions
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Expression Host
Mammalian
Reconstitution
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping Condition
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed in the Storage field.
Storage Condition and Shelf Life
Lyophilized protein should be stored at < -20C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20C for 3 months.
Background
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.
Analyte
B7-H4
Regulatory Status
For Research Use Only
