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Canine CAV-1 (Caveolin-1) ELISA Kit
Canine CAV-1 (Caveolin-1) ELISA Kit
The Canine (CAV-1) Caveolin-1 ELISA Kit measures Caveolin-1 in Canine samples. The plate has been pre-coated with Canine CAV1 antibody. CAV1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Canine CAV1 Antibody is added and binds to CAV1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CAV1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Canine CAV1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E0012Ca
Regular price
$618.00 USD
Regular price
$475.00 USD
Sale price
$618.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Canine
Sensitivity
10.68 pg/mL
Detection Range
20-6000 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity). Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity). Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Caveolin-1
Regulatory Status
For Research Use Only
