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CD68 Mouse mAb

CD68 Mouse mAb

The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.

Catalog No: EM1050
Regular price $148.00 USD
Regular price Sale price $148.00 USD
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Packaging
1.5 weeks
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Product Details

Application(s) IHC
Species Reactivity Human, Rat, Mouse
Source Murine
Isotype IgG1
Immunogen Synthetic Peptide
Concentration 1 mg/mL
Dilution IHC 1:200
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20C. Avoid repeated freeze-thaw cycles.
Analyte CD68
Regulatory Status For Research Use Only
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