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Claudin-2 (8H11) Mouse mAb
Claudin-2 (8H11) Mouse mAb
The claudin family is composed of 23 integral membrane proteins, and their expression, which varies among tissue types, may determine both the strength and properties of the epithelial barrier. Alteration in claudin protein expression pattern is associated with several types of cancer . Claudin-2 is expressed primarily in the proximal tubule of the normal mammalian kidney, where it regulates transepithelial ion (e.g., Na+, Cl-) reabsorption . Increased expression of Claudin-2 has been reported in some cancer cell lines , including A549 lung adenocarcinoma cells, where its nuclear distribution was positively associated with enhanced proliferation .
Catalog No:
EM1403
Regular price
$148.00 USD
Regular price
Sale price
$148.00 USD
Unit price
/
per
1.5 weeks
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Product Details
Application(s)
WB, IHC
Species Reactivity
Human, Rat, Mouse
Source
Murine
Isotype
IgG1
Immunogen
Synthetic Peptide
Concentration
1 mg/mL
Dilution
WB 1:1,000-2,000 IHC:1;100-1:200
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20C. Avoid repeated freeze-thaw cycles.
Analyte
Claudin-2
Regulatory Status
For Research Use Only
