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EGFR Mouse mAb
EGFR Mouse mAb
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades.
Catalog No:
EM1134
Regular price
$148.00 USD
Regular price
Sale price
$148.00 USD
Unit price
/
per
1.5 weeks
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Product Details
Application(s)
WB, IHC, IF, IP
Species Reactivity
Human
Source
Murine
Isotype
IgG1
Immunogen
Synthetic Peptide
Concentration
1 mg/mL
Dilution
WB 1:1,000-3,000 IP 1:200 IF 1:100-200
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20C. Avoid repeated freeze-thaw cycles.
Analyte
EGFR
Regulatory Status
For Research Use Only


