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EGFR Mouse mAb

EGFR Mouse mAb

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades.

Catalog No: EM1134
Regular price $148.00 USD
Regular price Sale price $148.00 USD
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Packaging
1.5 weeks
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Product Details

Application(s) WB, IHC, IF, IP
Species Reactivity Human
Source Murine
Isotype IgG1
Immunogen Synthetic Peptide
Concentration 1 mg/mL
Dilution WB 1:1,000-3,000 IP 1:200 IF 1:100-200
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20C. Avoid repeated freeze-thaw cycles.
Analyte EGFR
Regulatory Status For Research Use Only
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