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Human 5-Demethoxyubiquinone Hydroxylase Mitochondrial (COQ7) ELISA Kit
Human 5-Demethoxyubiquinone Hydroxylase Mitochondrial (COQ7) ELISA Kit
This ELISA kit is designed to detect Human 5-Demethoxyubiquinone Hydroxylase Mitochondrial (Human COQ7). The assay plate has been pre-coated with mouse anti-Human COQ7 monoclonal antibody. When the sample containing COQ7 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human COQ7 Antibody is added to the wells and binds to COQ7 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human COQ7 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE247
Regular price
$754.00 USD
Regular price
$580.00 USD
Sale price
$754.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
14.26 pg/mL
Detection Range
39.06-2500 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Metabolism, Signal Transduction
Background
Ubiquinone biosynthesis protein COQ7 homolog, also known as Coenzyme Q biosynthesis protein 7 homolog, Timing protein clk-1 homolog and COQ7, is a mitochondrion inner membrane and peripheral membrane protein which belongs to theCOQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. This enzyme is responsible for the hydroxylation of 5-demethoxyubiquinone to 5-hydroxyubiquinone. Human COQ7 protein is mostly helical, and contains an alpha-helical membrane insertion. It has a potential N-glycosylation site, a phosphorylation site for protein kinase C and another for casein kinase II, and three N-myristoylation sites. COQ7 is involved in lifespan determination in ubiquinone-independent manner. It is also involved in ubiquinone biosynthesis. COQ7 is potential central metabolic regulator.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
5-demethoxyubiquinone hydroxylase, mitochondrial
Regulatory Status
For Research Use Only
