1
/
of
1
Human BIN1 (Myc Box-dependent-interacting Protein 1) ELISA Kit
Human BIN1 (Myc Box-dependent-interacting Protein 1) ELISA Kit
The Human (BIN1) Myc Box-dependent-interacting Protein 1 ELISA Kit measures Myc Box-Dependent-Interacting Protein 1 in samples. The plate has been pre-coated with Human BIN1 antibody. BIN1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human BIN1 Antibody is added and binds to BIN1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated BIN1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human BIN1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2847Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
Couldn't load pickup availability
Product Details
Species Reactivity
Human
Sensitivity
9.97 ng/L
Detection Range
20-3800 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Cancer
Background
Is a key player in the control of plasma membrane curvature, membrane shaping and membrane remodeling. Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling (PubMed: 2$475.00|$350.005653). Is a negative regulator of endocytosis (By similarity). Is also involved in the regulation of intracellular vesicles sorting, modulation of BACE1 trafficking and the control of amyloid-beta production (PubMed: 27179792). In neuronal circuits, endocytosis regulation may influence the internalization of PHF-tau aggregates (By similarity). May be involved in the regulation of MYC activity and the control cell proliferation (PubMed: 8782822). Has actin bundling activity and stabilizes actin filaments against depolymerization in vitro (PubMed: 28893863). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Myc Box-Dependent-Interacting Protein 1
Regulatory Status
For Research Use Only
