1
/
of
1
Human CASQ1 (Calsequestrin-1) ELISA Kit
Human CASQ1 (Calsequestrin-1) ELISA Kit
The Human (CASQ1) Calsequestrin-1 ELISA Kit measures Calsequestrin-1 in samples. The plate has been pre-coated with Human CASQ1 antibody. CASQ1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human CASQ1 Antibody is added and binds to CASQ1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CASQ1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human CASQ1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E6588Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
Couldn't load pickup availability
Product Details
Species Reactivity
Human
Sensitivity
6.99 ng/L
Detection Range
15-3000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle (PubMed:28895244).
Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca2+ ions (PubMed:28895244).
Regulates the release of lumenal Ca2+ via the calcium release channel RYR1; this plays an important role in triggering muscle contraction. Negatively regulates store-operated Ca2+ entry (SOCE) activity (PubMed:27185316). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Calsequestrin-1
Regulatory Status
For Research Use Only
