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Human CFL1 (Cofilin-1) ELISA Kit
Human CFL1 (Cofilin-1) ELISA Kit
The Human (CFL1) Cofilin-1 ELISA Kit measures Cofilin-1 in samples. The plate has been pre-coated with Human CFL1 antibody. CFL1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human CFL1 Antibody is added and binds to CFL1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CFL1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human CFL1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E4625Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
7.96 ng/L
Detection Range
15-3000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (PubMed: 11812157). In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (PubMed: 15580268). Required for the centralization of the mitotic spindle and symmetric division of zygotes (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells (PubMed: 2183$498.00|$360.007). Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed: 23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Cofilin-1
Regulatory Status
For Research Use Only
