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Human CILP (Cartilage Intermediate Layer Protein 1) ELISA Kit
Human CILP (Cartilage Intermediate Layer Protein 1) ELISA Kit
The Human (CILP) Cartilage Intermediate Layer Protein 1 ELISA Kit measures Cartilage Intermediate Layer Protein 1 in samples. The plate has been pre-coated with Human CILP antibody. CILP present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human CILP Antibody is added and binds to CILP in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CILP antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human CILP. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E6610Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
26.34 ng/L
Detection Range
50-10000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Cartilage Intermediate Layer Protein 1
Regulatory Status
For Research Use Only
