1
/
of
1
Human CLDN10 (Claudin 10) ELISA Kit
Human CLDN10 (Claudin 10) ELISA Kit
The Human (CLDN10) Claudin 10 ELISA Kit measures Claudin 10 in samples. The plate has been pre-coated with Human CLDN10 antibody. CLDN10 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human CLDN10 Antibody is added and binds to CLDN10 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CLDN10 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human CLDN10. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2308Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
Couldn't load pickup availability
Product Details
Species Reactivity
Human
Sensitivity
0.051 ng/mL
Detection Range
0.1-35 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in the regulation of paracellular epithelia permeability to ions in multiple organs. It acts as a paracellular ion channel probably forming permselective pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. In sweat glands and in the thick ascending limb (TAL) of Henle's loop in kidney, it controls paracellular sodium permeability which is essential for proper sweat production and renal function (PubMed:19383724, PubMed:28771254, PubMed:28686597). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Claudin 10
Regulatory Status
For Research Use Only
