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Human CLNK (Cytokine-dependent Hematopoietic Cell Linker) ELISA Kit
Human CLNK (Cytokine-dependent Hematopoietic Cell Linker) ELISA Kit
The Human (CLNK) Cytokine-dependent Hematopoietic Cell Linker ELISA Kit measures Cytokine-Dependent Hematopoietic Cell Linker in samples. The plate has been pre-coated with Human CLNK antibody. CLNK present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human CLNK Antibody is added and binds to CLNK in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CLNK antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human CLNK. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E4818Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.015 ng/mL
Detection Range
0.05-15 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
An adapter protein which plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B-cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation (By similarity). Together with FGR, it acts as a negative regulator of natural killer cell-activating receptors and inhibits interferon-gamma production (By similarity). Acts as a positive regulator of both T-cell receptor and natural killer T (NKT) cell receptor signaling in CD4-positive NKT cells (By similarity). Together with MAP4K1, it enhances CD3-triggered activation of T-cells and subsequent IL2 production (By similarity). May be involved in tumor necrosis factor induced cell death by promoting reactive oxidative species generation, and MLKL oligomerization, ultimately leading to necrosis (By similarity). Involved in phosphorylation of LAT (By similarity). May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Cytokine-Dependent Hematopoietic Cell Linker
Regulatory Status
For Research Use Only
