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Human CORO1C (Coronin 1C) ELISA Kit
Human CORO1C (Coronin 1C) ELISA Kit
The Human (CORO1C) Coronin 1C ELISA Kit measures Coronin 1C in samples. The plate has been pre-coated with Human CORO1C antibody. CORO1C present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human CORO1C Antibody is added and binds to CORO1C in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CORO1C antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human CORO1C. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2450Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
9.19 ng/L
Detection Range
20-6000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Cell Biology
Background
Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1 (PubMed: 25074804, PubMed: 25925950). Increases the presence of activated RAC1 at the leading edge of migrating cells (PubMed: 25074804, PubMed: 25925950). Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments (By similarity). Plays a role in endoplasmic reticulum-associated endosome fission: localizes to endosome membrane tubules and promotes recruitment of TMCC1, leading to recruitment of the endoplasmic reticulum to endosome tubules for fission (PubMed: 30220460). Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane (PubMed: 30220460). Required for normal cell proliferation, cell migration, and normal formation of lamellipodia (By similarity). Required for normal distribution of mitochondria within cells (By similarity). [Isoform 3]: Involved in myogenic differentiation. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Coronin 1C
Regulatory Status
For Research Use Only
