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Human CPNE1 (Copine 1) ELISA Kit
Human CPNE1 (Copine 1) ELISA Kit
The Human (CPNE1) Copine 1 ELISA Kit measures Copine 1 in samples. The plate has been pre-coated with Human CPNE1 antibody. CPNE1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human CPNE1 Antibody is added and binds to CPNE1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CPNE1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human CPNE1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2437Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.027 ng/mL
Detection Range
0.05-10 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes (PubMed: 14674885). Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner (PubMed: 14674885). Exhibits calcium-dependent phospholipid binding properties (PubMed: 9430674, PubMed: 19539605). Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner (PubMed: 23263657, PubMed: 25450385). May recruit target proteins to the cell membrane in a calcium-dependent manner (PubMed: 12522145). May function in membrane trafficking (PubMed: 9430674). Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit (PubMed: 18212740). Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL (PubMed: 18212740). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Copine 1
Regulatory Status
For Research Use Only
