1
/
of
1
Human CYP7B1 (25-Hydroxycholesterol 7-alpha-hydroxylase) ELISA Kit
Human CYP7B1 (25-Hydroxycholesterol 7-alpha-hydroxylase) ELISA Kit
The Human (CYP7B1) 25-Hydroxycholesterol 7-alpha-hydroxylase ELISA Kit measures 25-Hydroxycholesterol 7-Alpha-Hydroxylase in samples.
Catalog No:
E3861Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
Couldn't load pickup availability
Product Details
Species Reactivity
Human
Sensitivity
0.027 ng/mL
Detection Range
0.05-10 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Lipid and Metabolism, Metabolism
Background
A cytochrome P450 monooxygenase involved in neural cholesterol clearance through bile acid synthesis (PubMed: 25201972, PubMed: 10748047). Catalyzes 7-alpha hydroxylation of (24S)-hydroxycholesterol, a neural oxysterol that is metabolized to bile acids in the liver (PubMed: 25201972, PubMed: 10748047). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed: 25201972, PubMed: 10748047). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
25-Hydroxycholesterol 7-Alpha-Hydroxylase
Regulatory Status
For Research Use Only
