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Human DKK2 (Dickkopf-related Protein 2) ELISA Kit
Human DKK2 (Dickkopf-related Protein 2) ELISA Kit
The Human (DKK2) Dickkopf-related Protein 2 ELISA Kit measures Dickkopf-Related Protein 2 in samples. The plate has been pre-coated with Human DKK2 antibody. DKK2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human DKK2 Antibody is added and binds to DKK2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated DKK2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human DKK2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E5182Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.026 ng/mL
Detection Range
0.1-40 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Stem Cells
Background
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Dickkopf-Related Protein 2
Regulatory Status
For Research Use Only
