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Human Erythropoietin Receptor (EPOR) ELISA Kit
Human Erythropoietin Receptor (EPOR) ELISA Kit
This ELISA kit is designed to detect Human Erythropoietin Receptor (Human EPOR). The assay plate has been pre-coated with mouse anti-Human EPOR monoclonal antibody. When the sample containing EPOR is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human EPOR Antibody is added to the wells and binds to EPOR in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human EPOR present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE124
Regular price
$624.00 USD
Regular price
$480.00 USD
Sale price
$624.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.49 pg/mL
Detection Range
1.95-125 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Cardiovascular, Immunology, Signal Transduction, Stem cells
Background
Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Erythropoietin receptor
Regulatory Status
For Research Use Only
