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Human FCGR2B (Low Affinity Immunoglobulin Gamma Fc Region Receptor 2B) ELISA Kit

Human FCGR2B (Low Affinity Immunoglobulin Gamma Fc Region Receptor 2B) ELISA Kit

The Human (FCGR2B) Low Affinity Immunoglobulin Gamma Fc Region Receptor 2B ELISA Kit measures Low affinity immunoglobulin gamma Fc region receptor 2-b in samples. The plate has been pre-coated with Human FCGR2B antibody. FCGR2B present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human FCGR2B Antibody is added and binds to FCGR2B in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated FCGR2B antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human FCGR2B. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

Catalog No: E3905Hu
Regular price $595.00 USD
Regular price $458.00 USD Sale price $595.00 USD
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2.5 weeks
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Product Details

Species Reactivity Human
Sensitivity 0.13 ng/mL
Detection Range 0.3-90 ng/mL
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 1.5 hour(s)
Research Areas Immunology
Background Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. Source: UniProt Consortium (2025)
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life 2-8C
Analyte Low affinity immunoglobulin gamma Fc region receptor 2-b
Regulatory Status For Research Use Only
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