The Human (FLRT2) Leucine-rich Repeat Transmembrane Protein Flrt2 ELISA Kit measures Leucine-Rich Repeat Transmembrane Protein FLRT2 in samples. The plate has been pre-coated with Human FLRT2 antibody. FLRT2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human FLRT2 Antibody is added and binds to FLRT2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated FLRT2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human FLRT2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
BackgroundFunctions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis. Source: UniProt Consortium (2025)
Shipping ConditionShipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
AnalyteLeucine-Rich Repeat Transmembrane Protein FLRT2
