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Human GAS6 (Growth Arrest-specific Protein 6) ELISA Kit
Human GAS6 (Growth Arrest-specific Protein 6) ELISA Kit
The Human (GAS6) Growth Arrest-specific Protein 6 ELISA Kit measures Growth Arrest-Specific Protein 6 in samples. The plate has been pre-coated with Human GAS6 antibody. GAS6 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human GAS6 Antibody is added and binds to GAS6 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated GAS6 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human GAS6. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E3257Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.13 ng/mL
Detection Range
0.3-90 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Cardiovascular
Background
Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. (Microbial infection) Can bridge virus envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry by apoptotic mimicry (PubMed: 21501828). Plays a role in Dengue cell entry by apoptotic mimicry (PubMed: 23084921). Plays a role in Vaccinia virus cell entry by apoptotic mimicry (PubMed: 21501828). Plays a role in ebolavirus and marburgvirus cell entry by apoptotic mimicry (PubMed: 17005688). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Growth Arrest-Specific Protein 6
Regulatory Status
For Research Use Only
