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Human GM2A (Ganglioside Gm2 Activator) ELISA Kit
Human GM2A (Ganglioside Gm2 Activator) ELISA Kit
The Human (GM2A) Ganglioside Gm2 Activator ELISA Kit measures Ganglioside Gm2 Activator in samples. The plate has been pre-coated with Human GM2A antibody. GM2A present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human GM2A Antibody is added and binds to GM2A in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated GM2A antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human GM2A. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E5320Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
5.28 ng/L
Detection Range
10-2000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Metabolism
Background
The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3 (By similarity). Has cholesterol transfer activity (PubMed: 17552909). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Ganglioside Gm2 Activator
Regulatory Status
For Research Use Only
