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Human GRK6 (G Protein-coupled Receptor Kinase 6) ELISA Kit
Human GRK6 (G Protein-coupled Receptor Kinase 6) ELISA Kit
The Human (GRK6) G Protein-coupled Receptor Kinase 6 ELISA Kit measures G Protein-Coupled Receptor Kinase 6 in samples. The plate has been pre-coated with Human GRK6 antibody. GRK6 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human GRK6 Antibody is added and binds to GRK6 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated GRK6 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human GRK6. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E5312Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
34.11 ng/L
Detection Range
70-15000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction, Enzyme & Kinase
Background
Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
G Protein-Coupled Receptor Kinase 6
Regulatory Status
For Research Use Only
