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Human GSAP (Gamma-secretase Activating Protein) ELISA Kit
Human GSAP (Gamma-secretase Activating Protein) ELISA Kit
The Human (GSAP) Gamma-secretase Activating Protein ELISA Kit measures Gamma-Secretase Activating Protein in samples. The plate has been pre-coated with Human gSAP antibody. gSAP present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human gSAP Antibody is added and binds to gSAP in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated gSAP antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human gSAP. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E3675Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.023 ng/mL
Detection Range
0.05-40 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
Regulator of gamma-secretase activity, which specifically activates the production of amyloid-beta protein (amyloid-beta protein 40 and amyloid-beta protein 42), without affecting the cleavage of other gamma-secretase targets such has Notch. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Specifically promotes the gamma-cleavage of APP CTF-alpha (also named APP-CTF) by the gamma-secretase complex to generate amyloid-beta, while it reduces the epsilon-cleavage of APP CTF-alpha, leading to a low production of AICD. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Gamma-Secretase Activating Protein
Regulatory Status
For Research Use Only
