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Human HCN2 (Potassium, Sodium Hyperpolarization-activated Cyclic Nucleotide-gated Channel 2) ELISA Kit

Human HCN2 (Potassium, Sodium Hyperpolarization-activated Cyclic Nucleotide-gated Channel 2) ELISA Kit

The Human (HCN2) Potassium, Sodium Hyperpolarization-activated Cyclic Nucleotide-gated Channel 2 ELISA Kit measures Potassium,Sodium Hyperpolarization-activated Cyclic Nucleotide-gated Channel 2 in samples. The plate has been pre-coated with Human HCN2 antibody. HCN2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human HCN2 Antibody is added and binds to HCN2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated HCN2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human HCN2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

Catalog No: E4848Hu
Regular price $595.00 USD
Regular price $458.00 USD Sale price $595.00 USD
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2.5 weeks
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Product Details

Species Reactivity Human
Sensitivity 10.22 ng/L
Detection Range 20-4000 ng/L
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 1.5 hour(s)
Research Areas Neuroscience
Background Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Produces a large instantaneous current. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages (By similarity). Source: UniProt Consortium (2025)
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life 2-8C
Analyte Potassium,Sodium Hyperpolarization-activated Cyclic Nucleotide-gated Channel 2
Regulatory Status For Research Use Only
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