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Human HSD17B8 (Estradiol 17-beta-dehydrogenase 8) ELISA Kit
Human HSD17B8 (Estradiol 17-beta-dehydrogenase 8) ELISA Kit
The Human (HSD17B8) Estradiol 17-beta-dehydrogenase 8 ELISA Kit measures Estradiol 17-Beta-Dehydrogenase 8 in samples. The plate has been pre-coated with Human HSD17B8 antibody. HSD17B8 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human HSD17B8 Antibody is added and binds to HSD17B8 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated HSD17B8 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human HSD17B8. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E3327Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
12.09 ng/L
Detection Range
20-4500 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction, Endocrinology, Hormone Metabolism
Background
NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone (PubMed: 17978863). The heterotetramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed: 19571038, PubMed: 25203508). Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed: 25203508). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Estradiol 17-Beta-Dehydrogenase 8
Regulatory Status
For Research Use Only
