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Human Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3 (LILRA3) ELISA Kit
Human Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3 (LILRA3) ELISA Kit
This ELISA kit is designed to detect Human Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3 (Human LILRA3). The assay plate has been pre-coated with mouse anti-Human LILRA3 monoclonal antibody. When the sample containing LILRA3 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human LILRA3 Antibody is added to the wells and binds to LILRA3 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human LILRA3 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE273
Regular price
$754.00 USD
Regular price
$580.00 USD
Sale price
$754.00 USD
Unit price
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per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
47.35 pg/mL
Detection Range
156.25-10000 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Immunology
Background
ILT6, also known as LILRA3, belongs to the ILT family. In humans, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immunoglobulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Leukocyte immunoglobulin-like receptor subfamily A member 3
Regulatory Status
For Research Use Only
