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Human MX1 (Interferon-induced Gtp-binding Protein Mx1) ELISA Kit

Human MX1 (Interferon-induced Gtp-binding Protein Mx1) ELISA Kit

The Human (MX1) Interferon-induced Gtp-binding Protein Mx1 ELISA Kit measures Interferon-Induced Gtp-Binding Protein Mx1 in samples. The plate has been pre-coated with Human MX1 antibody. MX1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human MX1 Antibody is added and binds to MX1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated MX1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human MX1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

Catalog No: E5499Hu
Regular price $595.00 USD
Regular price $458.00 USD Sale price $595.00 USD
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2.5 weeks
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Product Details

Species Reactivity Human
Sensitivity 5.23 ng/L
Detection Range 10-2000 ng/L
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 1.5 hour(s)
Research Areas Immunology
Background Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium Channel activity of TRPCs. Source: UniProt Consortium (2025)
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life 2-8C
Analyte Interferon-Induced Gtp-Binding Protein Mx1
Regulatory Status For Research Use Only
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