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Human Nectin-2 (NECTIN2) ELISA Kit

Human Nectin-2 (NECTIN2) ELISA Kit

This ELISA kit is designed to detect Human Nectin-2 (Human NECTIN2). The assay plate has been pre-coated with mouse anti-Human Nectin-2 monoclonal antibody. When the sample containing Nectin-2 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human Nectin-2 Antibody is added to the wells and binds to Nectin-2 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human Nectin-2 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.

Catalog No: BPE005
Regular price $754.00 USD
Regular price $580.00 USD Sale price $754.00 USD
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Product Details

Species Reactivity Human
Sensitivity 4.04 pg/mL
Detection Range 15.625-1000 pg/mL
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 3.5 hour(s)
Research Areas Immunology, Microbiology
Background Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+ T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy.
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life This product can be stored at 2-8C.
Analyte Nectin-2
Regulatory Status For Research Use Only
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