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Human RTN4RL2 (Reticulon-4 Receptor-like 2) ELISA Kit
Human RTN4RL2 (Reticulon-4 Receptor-like 2) ELISA Kit
The Human (RTN4RL2) Reticulon-4 Receptor-like 2 ELISA Kit measures Reticulon-4 Receptor-Like 2 in samples. The plate has been pre-coated with Human RTN4RL2 antibody. RTN4RL2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human RTN4RL2 Antibody is added and binds to RTN4RL2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated RTN4RL2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human RTN4RL2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E6082Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.021 ng/mL
Detection Range
0.05-20 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Neuroscience
Background
Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity). Plays a functionally redundant role in postnatal brain development. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed: 22325200). Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed: 22325200). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Reticulon-4 Receptor-Like 2
Regulatory Status
For Research Use Only
