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Human RYR1 (Ryanodine Receptor 1) ELISA Kit
Human RYR1 (Ryanodine Receptor 1) ELISA Kit
The Human (RYR1) Ryanodine Receptor 1 ELISA Kit measures Ryanodine Receptor 1 in samples. The plate has been pre-coated with Human RYR1 antibody. RYR1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human RYR1 Antibody is added and binds to RYR1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated RYR1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human RYR1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1992Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.05 ng/mL
Detection Range
0.1-30 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
Calcium Channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules (PubMed: 11741831, PubMed: 16163667). Repeated very high-level exercise increases the open probability of the Channel and leads to Ca(2+) leaking into the cytoplasm (PubMed: 18268335). Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Ryanodine Receptor 1
Regulatory Status
For Research Use Only
