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Human STX1A (Syntaxin-1A) ELISA Kit
Human STX1A (Syntaxin-1A) ELISA Kit
The Human (STX1A) Syntaxin-1A ELISA Kit measures Syntaxin-1A in samples. The plate has been pre-coated with Human STX1A antibody. STX1A present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human STX1A Antibody is added and binds to STX1A in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated STX1A antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human STX1A. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E4672Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
5.11 ng/L
Detection Range
10-2000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Neuroscience
Background
Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis (PubMed: 26635000). Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final fusion. Participates in the calcium-dependent regulation of acrosomal exocytosis in sperm (PubMed: 23091057). Plays also an important role in the exocytosis of hormones such as insulin or glucagon-like Peptide 1 (GLP-1) (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Syntaxin-1A
Regulatory Status
For Research Use Only
