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Human TCHP (Trichoplein Keratin Filament-binding Protein) ELISA Kit
Human TCHP (Trichoplein Keratin Filament-binding Protein) ELISA Kit
The Human (TCHP) Trichoplein Keratin Filament-binding Protein ELISA Kit measures Trichoplein Keratin Filament-Binding Protein in samples. The plate has been pre-coated with Human TCHP antibody. TCHP present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human TCHP Antibody is added and binds to TCHP in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated TCHP antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human TCHP. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E6318Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
7.45 ng/L
Detection Range
15-3000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed: 15731013, PubMed: 18931701). Is a negative regulator of ciliogenesis (PubMed: 25270598). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Trichoplein Keratin Filament-Binding Protein
Regulatory Status
For Research Use Only
