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Human TLR-9 (Toll-like Receptor 9) ELISA Kit
Human TLR-9 (Toll-like Receptor 9) ELISA Kit
The Human (TLR-9) Toll-like Receptor 9 ELISA Kit measures Toll-Like Receptor 9 in samples. The plate has been pre-coated with Human TLR9 antibody. TLR9 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human TLR9 Antibody is added and binds to TLR9 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated TLR9 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human TLR9. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E0356Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
2.53 ng/L
Detection Range
5-1500 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Immunology, Signal Transduction
Background
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed: 11564765, PubMed: 17932028). Controls lymphocyte response to Helicobacter infection (By similarity). Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (PubMed: 23857366). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Toll-Like Receptor 9
Regulatory Status
For Research Use Only
