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Human TMC1 (Transmembrane Channel-like Protein 1) ELISA Kit
Human TMC1 (Transmembrane Channel-like Protein 1) ELISA Kit
The Human (TMC1) Transmembrane Channel-like Protein 1 ELISA Kit measures Transmembrane Channel-like protein 1 in samples. The plate has been pre-coated with Human TMC1 antibody. TMC1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human TMC1 Antibody is added and binds to TMC1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated TMC1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human TMC1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E6310Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
7.43 ng/L
Detection Range
15-3000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Neuroscience
Background
Transmembrane channel-like protein 1 is a protein that in humans is encoded by the TMC1 gene. TMC1 contains six transmembrane domains with both the C and N termini on the endoplasmic side of the membrane, as well as a large loop between domains 4 and 5. This topology is similar to that of transient receptor potential channels (TRPs), a family of proteins involved in the perception of senses such as temperature, taste, pressure, and vision. TMC1 has been located in the post-natal mouse cochlea, and knockouts for TMC1 and TMC2 result in both auditory and vestibular deficits (hearing loss and balance issues) indicating TMC1 is a molecular part of auditory transduction. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Transmembrane Channel-like protein 1
Regulatory Status
For Research Use Only
