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Human TRIP13 (Pachytene Checkpoint Protein 2 Homolog) ELISA Kit
Human TRIP13 (Pachytene Checkpoint Protein 2 Homolog) ELISA Kit
The Human (TRIP13) Pachytene Checkpoint Protein 2 Homolog ELISA Kit measures Pachytene Checkpoint Protein 2 Homolog in samples. The plate has been pre-coated with Human TRIP13 antibody. TRIP13 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human TRIP13 Antibody is added and binds to TRIP13 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated TRIP13 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human TRIP13. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1743Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
5.91 ng/L
Detection Range
10-2000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). Plays a role in mitotic spindle assembly checkpoint (SAC) activation (PubMed: 28553959). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Pachytene Checkpoint Protein 2 Homolog
Regulatory Status
For Research Use Only
