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Human UMOD (Uromodulin) ELISA Kit
Human UMOD (Uromodulin) ELISA Kit
The Human (UMOD) Uromodulin ELISA Kit measures Uromodulin in samples. The plate has been pre-coated with Human UMOD antibody. UMOD present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human UMOD Antibody is added and binds to UMOD in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated UMOD antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human UMOD. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E4743Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.51 ng/mL
Detection Range
1-400 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
[Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF (PubMed: 3$498.00|$360.00215). Facilitates neutrophil migration across renal epithelia (PubMed: 20798515). [Uromodulin, secreted form]: In the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and inhibits formation of liquid containing supersaturated salts and subsequent formation of salt crystals. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Uromodulin
Regulatory Status
For Research Use Only
