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Mouse BDNF (Brain Derived Neurotrophic Facor) ELISA Kit
Mouse BDNF (Brain Derived Neurotrophic Facor) ELISA Kit
The Mouse (BDNF) Brain Derived Neurotrophic Facor ELISA Kit measures Brain Derived Neurotrophic Facor in Mouse samples. The plate has been pre-coated with Mouse BDNF antibody. BDNF present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse BDNF Antibody is added and binds to BDNF in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated BDNF antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse BDNF. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E0013Mo
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Mouse
Sensitivity
0.021 ng/mL
Detection Range
0.05-10 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Neuroscience, Cardiovascular, Metabolism
Background
Important signaling molecule that activates signaling cascades downstream of NTRK2 (PubMed: 27457814). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability (PubMed: 8139657, PubMed: 15486301, PubMed: 17023662, PubMed: 27457814, PubMed: 29909994). [BDNF precursor form]: Important signaling molecule that activates signaling cascades downstream of NTRK2 (PubMed: 27457814). Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2 (PubMed: 24908487, PubMed: 29909994). Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD) (PubMed: 27457814). Binding to NGFR and SORCS2 promotes neuronal apoptosis (PubMed: 24908487). Promotes neuronal growth cone collapse (PubMed: 24908487, PubMed: 27457814). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Brain Derived Neurotrophic Facor
Regulatory Status
For Research Use Only
