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Mouse C-Reactive Protein (CRP) ELISA Kit

Mouse C-Reactive Protein (CRP) ELISA Kit

This ELISA kit is designed to detect Mouse C-Reactive Protein (Mouse CRP). The assay plate has been pre-coated with mouse anti-Mouse C-Reactive Protein monoclonal antibody. When the sample containing C-Reactive Protein is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Mouse C-Reactive Protein Antibody is added to the wells and binds to C-Reactive Protein in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Mouse C-Reactive Protein present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.

Catalog No: BPE318
Regular price $624.00 USD
Regular price $480.00 USD Sale price $624.00 USD
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Packaging
2 weeks
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Product Details

Species Reactivity Mouse
Sensitivity 7.78 pg/mL
Detection Range 39.06-2500 pg/mL
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 3.5 hour(s)
Research Areas Cardiovascular, Epigenetics and Nuclear Signaling, Immunology, Metabolism, Neuroscience
Background C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monitor many human diseases. However, CRP is likely to have important host defence, scavenging and metabolic functions through its capacity for calcium-dependent binding to exogenous and autologous molecules containing phosphocholine (PC) and then activating the classical complement pathway. CRP may also have pathogenic effects and the recent discovery of a prognostic association between increased CRP production and coronary atherothrombotic events is of particular interest.
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life This product can be stored at 2-8C.
Analyte C-reactive protein
Regulatory Status For Research Use Only
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