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Mouse CDH2 (Cadherin-2) ELISA Kit
Mouse CDH2 (Cadherin-2) ELISA Kit
The Mouse (CDH2) Cadherin-2 ELISA Kit measures Cadherin-2 in Mouse samples. The plate has been pre-coated with Mouse CDH2 antibody. CDH2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse CDH2 Antibody is added and binds to CDH2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CDH2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse CDH2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1892Mo
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Mouse
Sensitivity
14.35 ng/L
Detection Range
30-9000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell (PubMed: 2762814, PubMed: 11433297, PubMed: 17988630, PubMed: 9655503, PubMed: 25253890). Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence (PubMed: 24952463). Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (PubMed: 26750727). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Cadherin-2
Regulatory Status
For Research Use Only
