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Mouse CHI3L1 (Chitinase-3-like Protein 1) ELISA Kit
Mouse CHI3L1 (Chitinase-3-like Protein 1) ELISA Kit
The Mouse (CHI3L1) Chitinase-3-like Protein 1 ELISA Kit measures Chitinase-3-Like Protein 1 in Mouse samples. The plate has been pre-coated with Mouse CHI3L1 antibody. CHI3L1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse CHI3L1 Antibody is added and binds to CHI3L1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CHI3L1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse CHI3L1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1136Mo
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Mouse
Sensitivity
0.25 ng/mL
Detection Range
0.5-200 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Chitinase-3-Like Protein 1
Regulatory Status
For Research Use Only
