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Mouse CTSL1 (Cathepsin L1) ELISA Kit
Mouse CTSL1 (Cathepsin L1) ELISA Kit
The Mouse (CTSL1) Cathepsin L1 ELISA Kit measures Cathepsin L1 in Mouse samples. The plate has been pre-coated with Mouse CTSL antibody. CTSL present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse CTSL Antibody is added and binds to CTSL in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CTSL antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse CTSL. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1911Mo
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Mouse
Sensitivity
14.36 ng/L
Detection Range
30-9000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (PubMed: 12782676). In neuroendocrine chromaffin cells secretory vesicles, catalyzes the prohormone proenkephalin processing to the active enkephalin Peptide neurotransmitter (PubMed: 12869695). In thymus, regulates CD4(+) T cell positive selection by generating the major histocompatibility complex class II (MHCII) bound Peptide ligands presented by cortical thymic epithelial cells (PubMed: 12021314). Also mediates invariant chain processing in cortical thymic epithelial cells (PubMed: 9545226). Major elastin-degrading enzyme at neutral pH. Accumulates as a mature and active enzyme in the extracellular space of antigen presenting cells (APCs) to regulate degradation of the extracellular matrix in the course of inflammation (PubMed: 12417635). Secreted form generates endostatin from COL18A1 (PubMed: 10716919). Critical for cardiac morphology and function (PubMed: 11972068). Plays an important role in hair follicle morphogenesis and cycling, as well as epidermal differentiation (PubMed: 12163394). Required for maximal stimulation of steroidogenesis by TIMP1 (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Cathepsin L1
Regulatory Status
For Research Use Only
