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Mouse DKK3 (Dickkopf-3) ELISA Kit
Mouse DKK3 (Dickkopf-3) ELISA Kit
The Mouse (DKK3) Dickkopf-3 ELISA Kit measures Dickkopf-3 in Mouse samples. The plate has been pre-coated with Mouse DKK3 antibody. DKK3 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse DKK3 Antibody is added and binds to DKK3 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated DKK3 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse DKK3. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1212Mo
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Mouse
Sensitivity
0.02 ng/mL
Detection Range
0.5-20 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Stem Cells
Background
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Dickkopf-3
Regulatory Status
For Research Use Only
