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Mouse GGT1 (Gamma-Glutamyltranspeptidase 1) ELISA Kit
Mouse GGT1 (Gamma-Glutamyltranspeptidase 1) ELISA Kit
The Mouse (GGT1) Gamma-Glutamyltranspeptidase 1 ELISA Kit measures Gamma-Glutamyltranspeptidase 1 in Mouse samples. The plate has been pre-coated with Mouse GGT1 antibody. GGT1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse GGT1 Antibody is added and binds to GGT1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated GGT1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse GGT1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2090Mo
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Mouse
Sensitivity
0.112 mIU/mL
Detection Range
0.2-60 mIU/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates and other gamma-glutamyl compounds, such as leukotriene C4 (LTC4). The metabolism of glutathione by GGT1 releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Contributes to cysteine homeostasis, glutathione homeostasis and in the conversion of the leukotriene LTC4 to LTD4 (By similarity). Indirectly regulates multiple aspects of skeletal biology (PubMed: 12810527). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Gamma-Glutamyltranspeptidase 1
Regulatory Status
For Research Use Only
