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Mouse IL-21 (Interleukin 21) ELISA Kit
Mouse IL-21 (Interleukin 21) ELISA Kit
The Mouse (IL-21) Interleukin 21 ELISA Kit measures Interleukin 21 in Mouse samples. The plate has been pre-coated with Mouse IL21 antibody. IL21 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse IL21 Antibody is added and binds to IL21 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated IL21 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse IL21. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E0614Mo
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Mouse
Sensitivity
4.55 ng/L
Detection Range
10-2000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Immunology, Cancer, Cytokines, Inflammation
Background
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (PubMed: 15100251). Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (PubMed: 23045607). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15 (PubMed: 11970879). May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (PubMed: 12893770). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Interleukin 21
Regulatory Status
For Research Use Only
