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Mouse ITLN1/OMENTIN (Intelectin-1) ELISA Kit
Mouse ITLN1/OMENTIN (Intelectin-1) ELISA Kit
The Mouse (ITLN1/OMENTIN) Intelectin-1 ELISA Kit measures Intelectin-1 in Mouse samples. The plate has been pre-coated with Mouse ITSN1 antibody. ITSN1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse ITSN1 Antibody is added and binds to ITSN1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated ITSN1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse ITSN1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E0145Mo
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Mouse
Sensitivity
0.57 ng/mL
Detection Range
1-380 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery (PubMed: 1006$458.00|$300.003). Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (By similarity). Plays a role in the assembly and maturation of clathrin-coated vesicles (By similarity). Recruits FCHSD2 to clathrin-coated pits (By similarity). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors (PubMed: 16914641). Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2 (By similarity). Promotes ubiquitination and subsequent degradation of EGFR, and thereby contributes to the down-regulation of EGFR-dependent signaling pathways (PubMed: 16914641). In chromaffin cells, required for normal exocytosis of catecholamines (PubMed: 18676989). Required for rapid replenishment of release-ready synaptic vesicles at presynaptic active zones (PubMed: 23633571). Inhibits ARHGAP31 activity toward RAC1 (By similarity). [Isoform 1]: Plays a role in synaptic vesicle endocytosis in brain neurons. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Intelectin-1
Regulatory Status
For Research Use Only
