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Mouse KISS1 (Metastasis-Suppressor Kiss-1) ELISA Kit
Mouse KISS1 (Metastasis-Suppressor Kiss-1) ELISA Kit
The Mouse (KISS1) Metastasis-Suppressor Kiss-1 ELISA Kit measures Metastasis-Suppressor Kiss-1 in Mouse samples. The plate has been pre-coated with Mouse KISS1 antibody. KISS1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse KISS1 Antibody is added and binds to KISS1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated KISS1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse KISS1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2253Mo
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Mouse
Sensitivity
3.45 ng/L
Detection Range
7-1500 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Cancer
Background
Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated Peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. Intracerebroventricular administration induces an increase in serum LH and FSH levels in prepubertal male and female as well as in adult animals. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Metastasis-Suppressor Kiss-1
Regulatory Status
For Research Use Only
