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Mouse NKX2-1 (Homeobox Protein Nkx-2.1) ELISA Kit

Mouse NKX2-1 (Homeobox Protein Nkx-2.1) ELISA Kit

The Mouse (NKX2-1) Homeobox Protein Nkx-2.1 ELISA Kit measures Homeobox Protein Nkx-2.1 in Mouse samples. The plate has been pre-coated with Mouse NKX2-1 antibody. NKX2-1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse NKX2-1 Antibody is added and binds to NKX2-1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated NKX2-1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse NKX2-1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

Catalog No: E1426Mo
Regular price $595.00 USD
Regular price $458.00 USD Sale price $595.00 USD
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2.5 weeks
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Product Details

Species Reactivity Mouse
Sensitivity 0.033 ng/mL
Detection Range 0.05-30 ng/mL
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 1.5 hour(s)
Background Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation (PubMed: 22955271). Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (PubMed: 22356123). Source: UniProt Consortium (2025)
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life 2-8C
Analyte Homeobox Protein Nkx-2.1
Regulatory Status For Research Use Only
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