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Mouse Polymeric Immunoglobulin Receptor (PIGR) ELISA Kit
Mouse Polymeric Immunoglobulin Receptor (PIGR) ELISA Kit
This ELISA kit is designed to detect Mouse Polymeric Immunoglobulin Receptor (Mouse PIGR). The assay plate has been pre-coated with mouse anti-Mouse PIGR monoclonal antibody. When the sample containing PIGR is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Mouse PIGR Antibody is added to the wells and binds to PIGR in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Mouse PIGR present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE293
Regular price
$754.00 USD
Regular price
$580.00 USD
Sale price
$754.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Mouse
Sensitivity
3.09 pg/mL
Detection Range
7.81-500 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Immunology
Background
Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Polymeric immunoglobulin receptor
Regulatory Status
For Research Use Only
